BDBM50188372 4-(4-fluoro-phenyl)-8-(2-hydroxy-2-m-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL214257

SMILES Cc1cccc(c1)C1(O)CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1

InChI Key InChIKey=UYYIDOZWUDXOBN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188372   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188372(4-(4-fluoro-phenyl)-8-(2-hydroxy-2-m-tolyl-cyclohe...)
Affinity DataEC50:  2.64E+3nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed